What Is Pancreatitis, Pancreatitis Symptoms, Causes And Treat Pancreatitis

Pancreatitis Definition - Pancreatitis is a condition of inflammation that cause pain where the pancreatic enzyme are activated in premature resulted in auto digestive from pancreas. may be acute or chronic pancreatitis with symptoms of severe or mild symptoms.

pancreatitis is a serious disease of the pancreas with an intensity that can range from relatively mild disorders and healed himself until the disease that runs fast and fatal that does not react to various treatment.

acute pancreatitis is a process of acute inflammation of the pancreas is about and is chracterized by varying degrees of edema, hemorrhage and necrosis in the ACINI cells and blood vessels.

Anatomy Physiology Pancreatic Gland

pancreatic gland-gland lies behind the stomach in front of the lumbar vertebrae 1 and 2, composed of cells of alpha and beta. alpha cells produce the hormone glucagon, while beta cells produce the hormone insulin. the hormone insulin is a hormone that is administered takes part of the protein.

12 Symptoms And Signs Of Pancreatitis

great up penetrate the abdominal pain lower back
abdominal distention
vomiting
bloating
there are ekimosis
bleeding
hot
agitation in weight loss
hypo tension
takipneu
pain abdominal press

Causes Of Pancreatitis Or Pancreatitis Etiology

a. Metabolic :

alcoholism
hyperlipoproteinemia
hyperlaksemia
drugs (for example : diuretic ti-acid)
genetic

b. Mechanical

trauma
gallstones
latrogenic jejas
jejas perioperatif
endoscopic produces with injecting a substance the color

c. Vascular :

shock
atheroembolisme
poliarteritis nodusa

d. Infection :

parotitis (in)
Cossack virus
mycoplasma pneumonia

Pathophysiology Of Pancreatic

pancreas be secretion a number of enzymes : amylase and lipase secreted in the form of temporary active pro-tease, elastase and p hospholipase secreted as pro-enzymes which under normal circumstances has to be activated by trypsin in the duodenum, trypsin itself normally in active by duodenal.

parthenogenesis of acute pancreatitis is centered on the activities of trypsin is not appropriate in the pancreas, the active trypsin activates the kin-in system as well as a clotting. the net-to results in the form of pancreatic inflammation and thrombosis, the characteristics of proteolysis include pancreatitis tissues, lipolysis, and bleeding occurs because the destructive pancreatic enzymes released from the cells assigner.

The Mechanism Proposed For The Activity Of Enzymes Of The Pancreas Include The Following :

1. Pancreatic Duct Obstruction

IE gallstone can be sandwiched in the ampule artery on proximal obstruction, enzyme rich fluid accumulates and raises jajes pancreatic parenkim, leukocytes in the network parenkim will loses proimflamatoric cytokines that promote local inflammation and edema.

2. Primary Jejas Cell Assigner

this situation can be caused by damage due to virus (parotitis), drugs, trauma or ischemia

3. The Septal Transformation Extracellular Pro enzymes

is exorin enzymes of the pancreas are experiencing errors in direction, i.e. towards the Lysosomes and leading to secretion, hydrolysis of the pro-enzymes in the lysosomes activity and will cause the release of enzymes.

4. Alcohol

alcohol can increase the jejas cells intro-cellular pro-enzymes ride assigner passing in the wrong direction and the blockage of protein deposition of thickened and multiply inside the ducts so pancreatic inflammation and local obstruction.

5. Hereditary Pancreatitis

marked by great pancreatitis rekuen moans and has already started since the age of the children. the disorder is caused by mutations of the gene line (line-derived cell buds) on :

a. gentripsinogen cat-ionic (PRSSI) cause lost somewhere on the inactivation of trypsin enzyme essential for itself (an important security mechanism to regulate the activity of the enzyme trypsin).

b. serine pro-tease inhibitor gene, kazal type I (SPINK I) which give rise to proteins that are defective so that it is no longer capable of showing the activity of trypsin.

the pancreas undergoes destruction anatomically and functionally replace proresit, with pancreas cells (cells of pancreatic assigner) normal connective tissue, the result of an attack of pancreatitis over and over again and the toxic effects of alcohol and the metabolite, then pressure in the pancreas will increase.

the end result is the mechanical obstruction of the duct pancreatic, koledokus and duodenum, besides it will happen anyway such duct epithelial atrophy, inflammation and destruction of pancreatic cells that carry out the functions of the endocrine secretion of (parenkim destruction the pancreas).

10 Complication Of Pancreatitis

ha-emo-dynamic instability to shock
pleural effusion
acute renal failure
hyperglycemia
acidosis
hyperglycemia
hypomagnesemia
bleeding pancreas
infected necrosis
obstruction column accompanied by necrosis.

What Is Pancreatitis, Pancreatitis Symptoms, Causes And Treat Pancreatitis